PPS – Flagged Problematic Cell Lines

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‘Problematic Cell Lines’ Detector

This detector is still under development. It tabulates:

A sample of COVID19 articles matched against the ICLAC Register of Misidentified Cell Lines.
Articles featuring 7 non-verifiable cell lines: BGC-803, BSG-803, BSG-823, GSE-1, HGC-7901, HGC-803, and MGC-823.

📄 Oste, D.J., Pathmendrea, P., Richardson, R.A.K., …, J.A. Byrne (2024). Misspellings or “miscellings”—Non-verifiable and unknown cell lines in cancer research publications.
International Journal of Cancer. https://doi.org/10.1002/ijc.34995
▷ Filter the table below and show the cases reported in this preprint.

⏰ Last Update: 2026-05-20 at 08:14

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Oste et al

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Year	Doctype	Publisher	Venue	Title	DOI	Citations	Altmetric	TipsDescending	Concern	Assessor	PubPeer Users
2021	article	Wiley	The Journal of Gene Medicine	RETRACTED: Long non‐coding RNA KCNQ1OT1 promotes the progression of gastric cancer via the miR‐145‐5p/ARF6 axis	10.1002/jgm.3330	20	0	6	BGC803 • BSG803 • BSG823 • GSE-1 • GSE1 • See (Oste et al., 2024)	Cabanac	Amos Bairoch, Hoya Camphorifolia
1988	article	Chinese Journal of Cancer Research	Chinese Journal of Cancer Research	Production of antitumor human monoclonal antibodies by human-human or mouse-human hybridoma	10.1007/bf02997636	0	0	2	MGC-823 • See (Oste et al., 2024)		–
2015	article	Public Library of Science (PLoS)	PLOS ONE	RETRACTED > MicroRNA-137 Contributes to Dampened Tumorigenesis in Human Gastric Cancer by Targeting AKT2	10.1371/journal.pone.0130124	33	2	2	HGC-803 • See (Oste et al., 2024)	Cabanac	Campanula Pseudostenocodon, Hoya Camphorifolia
2014	article	Springer Nature	Oncogene	MicroRNA-25 promotes gastric cancer migration, invasion and proliferation by directly targeting transducer of ERBB2, 1 and correlates with poor survival	10.1038/onc.2014.214	125	0	2	HGC-7901 • See (Oste et al., 2024)	Invitation for human assessors	Mycosphaerella Arachidis
2021	article	Springer Nature	Cell Death & Disease	STIM1 promotes angiogenesis by reducing exosomal miR-145 in breast cancer MDA-MB-231 cells	10.1038/s41419-020-03304-0	57	0	1	See (Oste et al., 2024)		–
2021	article	Springer Nature	Cancer Cell International	Circular RNA hsa_circ_0003288 induces EMT and invasion by regulating hsa_circ_0003288/miR-145/PD-L1 axis in hepatocellular carcinoma	10.1186/s12935-021-01902-2	54	2	1	See (Oste et al., 2024)		–
2019	article	Oxford University Press (OUP)	Clinical & Experimental Immunology	Cisplatin-mediated down-regulation of miR-145 contributes to up-regulation of PD-L1 via the c-Myc transcription factor in cisplatin-resistant ovarian carcinoma cells	10.1111/cei.13406	52	1	1	See (Oste et al., 2024)		–
2020	article	Impact Journals	Aging	Circular RNA hsa_circ_0000073 contributes to osteosarcoma cell proliferation, migration, invasion and methotrexate resistance by sponging miR-145-5p and miR-151-3p and upregulating NRAS	10.18632/aging.103423	49	1	1	See (Oste et al., 2024)		–
2019	article	Spandidos Publications	International Journal of Oncology	lncRNA CCAT2 promotes radiotherapy resistance for human esophageal carcinoma cells via the miR-145/p70S6K1 and p53 pathway	10.3892/ijo.2019.4929	48	0	1	See (Oste et al., 2024)		–
2018	article	–	American Journal of Translational Research	The FENDRR/miR-214-3P/TET2 axis affects cell malignant activity via RASSF1A methylation in gastric cancer.	–	47	0	1	See (Oste et al., 2024)		–
2020	article	Taylor & Francis	OncoTargets and Therapy	Elevated Levels of circRUNX1 in Colorectal Cancer Promote Cell Growth and Metastasis via miR-145-5p/IGF1 Signalling	10.2147/ott.s254133	37	0	1	See (Oste et al., 2024)		–
2020	article	–	European review for medical and pharmacological sciences	The reduced lncRNA NKILA inhibited proliferation and promoted apoptosis of chondrocytes via miR-145/SP1/NF-κB signaling in human osteoarthritis.	10.26355/eurrev_202001_20030	30	0	1	See (Oste et al., 2024)		–
2021	article	Frontiers	Frontiers in Cell and Developmental Biology	CircCDYL Acts as a Tumor Suppressor in Wilms’ Tumor by Targeting miR-145-5p	10.3389/fcell.2021.668947	27	1	1	See (Oste et al., 2024)		–
2016	article	Bentham Science Publishers	Recent Patents on Anti-Cancer Drug Discovery	Decreased Expression of Caveolin-1 and E-Cadherin Correlates with the Clinicopathologic Features of Gastric Cancer and the EMT Process.	10.2174/1574892811666160128151437	27	0	1	See (Oste et al., 2024)		–
2020	article	Taylor & Francis	OncoTargets and Therapy	miR-145-5p Regulates the Proliferation, Migration and Invasion in Cervical Carcinoma by Targeting KLF5	10.2147/ott.s241366	22	0	1	See (Oste et al., 2024)		–
2020	article	Taylor & Francis	Cell Cycle	Long non-coding RNA CASC9 promotes the progression of retinoblastoma via interacting with miR-145-5p	10.1080/15384101.2020.1802813	16	0	1	See (Oste et al., 2024)		–
2022	article	Springer Nature	Functional & Integrative Genomics	Knockdown of circMYOF inhibits cell growth, metastasis, and glycolysis through miR-145-5p/OTX1 regulatory axis in laryngeal squamous cell carcinoma	10.1007/s10142-022-00862-8	16	0	1	See (Oste et al., 2024)		–
2022	article	Taylor & Francis	Bioengineered	CircMYC promotes proliferation, migration, invasion and inhibits apoptosis of small cell lung cancer by targeting miR-145/ Matrix Metallopeptidase 2 axis	10.1080/21655979.2022.2062978	13	2	1	See (Oste et al., 2024)		–
2003	article	BMJ	Molecular Pathology	Regions of allelic imbalance in the distal portion of chromosome 12q in gastric cancer	10.1136/mp.56.3.141	13	6	1	See (Oste et al., 2024)		–
2020	article	African Journals Online (AJOL)	Tropical Journal of Pharmaceutical Research	Cinnamic hydroxamic acid inhibits the proliferation of gastric cancer cells via upregulation of miR 145 expression and down-regulation of P13K/Akt signaling pathway	10.4314/tjpr.v19i5.7	12	0	1	See (Oste et al., 2024)		–

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