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| N/A | 10.2139/ssrn.4409350 | 1 | 07/04/2023 | Safety, Immunogenicity and Efficacy of Heterologous Boost with an Aerosolized Ad5-nCoV after Two-Dose Priming with Inactivated COVID-19 Vaccines in Adults: A Multicenter, Open-Label Trial | Li, Jing-Xin; Hou, Li-Hua; Gou, Jin-Bo; Jia, Si-Yue; Yin, Zun-Dong; Tang, Rong; Wu, Shi-Po; Wang, Fu-Zhen; Zhang, Zhe; Pan, Hong-Xing; Zhang, Li; Xu, Jia-Wei; Peng, Zhi-Hang; Tang, Ji-Hai; Wang, Qing; Xu, Qing; Zheng, Yan; Huang, Tao; Li, Tao; Liu, Shu-Jun; Wang, Cang-Ning; Zhu, Tao; Shen, Hong-Bing; Chen, Wei; Zhu, Feng-Cai | | initial deposit | - |
| medRxiv | 10.1101/2023.03.24.23287658 | 1 | 29/03/2023 | Safety and Immunogenicity of the NVX-CoV2373 Vaccine as a Booster in Adults Previously Vaccinated with the BBIBP-CorV Vaccine: An Interim Analysis | Toback, S.; Marchese, A. M.; Warren, B.; Ayman, S.; Zarkovic, S.; ElTantawy, I.; Mallory, R. M.; Rousculp, M.; Almarzooqi, F.; Piechowski-Jozwiak, B.; Bonilla, M.-F.; Bakkour, A. E.; Hussein, S. E.; Al Kaabi, N. | | publishaheadofprint | - |
| Research Square | 10.21203/rs.3.rs-2549560/v1 | 1 | 04/02/2023 | A randomized, controlled study to evaluate the safety and immunogenicity of a heterologous booster dose of an adjuvanted SARS CoV-2 recombinant spike protein vaccine in adults | Kulkarni, Prasad; Gunale, Bhagwat; Kohli, Sunil; Lalwani, Sanjay; Tripathy, Srikanth; Kar, Sonali; Raut, Sidram; Kulkarni, Praveen; Apte, Aditi; Bavdekar, Ashish; Bhalla, Hira Lal; Plested, Joyce; Cloney-Clark, Shane; Zhu, MingZhu; Kalkeri, Raj; Pryor, Melinda; Hamilton, Stephanie; Thakar, Madhuri; Sannidhi, Ranga; Baranwal, Punjita; Bhamare, Chetanraj; Dharmadhikari, Abhijeet; Gupta, Manish; Poonawalla, Cyrus; Shaligram, Umesh; Kapse, Dhananjay | | initial deposit | - |
| medRxiv | 10.1101/2023.01.31.23285306 | 2 | 02/02/2023 | Immunogenicity of the BA.1 and BA.4/5 Bivalent Boosts: A Brief Report of Preliminary Results from the COVAIL Randomized Clinical Trial | Branche, A. R.; Rouphael, N.; Losada, C.; Baden, L. R.; Anderson, E. J.; Luetkemeyer, A. F.; Diemert, D. J.; Winokur, P. L.; Presti, R. M.; Kottkamp, A. C.; Falsey, A. R.; Frey, S. E.; Rupp, R.; Backer, M.; Novak, R. M.; Walter, E. B.; Jackson, L. A.; Little, S. J.; Immergluck, L. C.; Mahgoub, S. M.; Whitaker, J. A.; Babu, T. M.; Goepfert, P. A.; Fusco, D. N.; Atmar, R. L.; Posavad, C. M.; Netzl, A.; Smith, D. J.; Telu, K.; Mu, J.; Matkowski, M.; Makhene, M.; Crandon, S.; Montefiori, D. C.; Roberts, P. C.; Beigel, J. H. | 10.1093/cid/ciad209 | publishaheadofprint | CRESS, medRxiv |
| N/A | 10.2139/ssrn.4090492 | 1 | 31/01/2023 | Safety and Immunogenicity of an Inactivated Whole Virion SARS-CoV-2 Vaccine, TURKOVAC, in Healthy Adults: Interim Results from Randomised, Double-Blind, Placebo-Controlled Phase 1 and 2 Trials | Ozdarendeli, Aykut; Sezer, Zafer; Pavel, Shaikh Terkis Islam; Inal, Ahmet; Yetiskin, Hazel; Kaplan, Busra; Uygut, Muhammet Ali; Bayram, Adnan; Mazicioglu, Mumtaz; Kalin Unuvar, Gamze; Ture Yuce, Zeynep; Aydin, Guncu; Aslan, Ahmet Furkan; Kaya, Refika Kamuran; Koc, Rabia Cakir; Kara, Ates | | initial deposit | - |
| N/A | 10.2139/ssrn.4309025 | 1 | 26/01/2023 | Safety and Immunogenicity of SARS-CoV-2 Self-Amplifying RNA Vaccine Expressing Anchored RBD: A Randomised, Observer-Blind, Phase 1 Study | Akahata, Wataru; Sekida, Takashi; Nogimori, Takuto; Ode, Hirotaka; Tamura, Tomokazu; Kono, Kaoru; Kazami, Yoko; Washizaki, Ayaka; Masuta, Yuji; Suzuki, Rigel; Matsuda, Kenta; Komori, Mai; Morey, Amber; Ishimoto, Keiko; Nakata, Misako; Hasunuma, Tomoko; Fukuhara, Takasuke; Iwatani, Yasumasa; Yamamoto, Takuya; Smith, Jonathan F.; Sato, Nobuaki | | initial deposit | - |
| medRxiv | 10.1101/2023.01.24.23284869 | 2 | 24/01/2023 | A Randomized Trial Comparing Omicron-Containing Boosters with the Original Covid-19 Vaccine mRNA-1273 | Lee, I. T.; Cosgrove, C. A.; Moore, P.; Bethune, C.; Nally, R.; Bula, M.; Kalra, P. A.; Clark, R.; Dargan, P.; Boffito, M.; Sheridan, R.; Moran, E.; Darton, T. C.; Burns, F.; Saralaya, D.; Duncan, C. J. A.; Lillie, P.; Ramos, A. S. F.; Galiza, E.; Heath, P. T.; Chalkias, S.; Girard, B.; Parker, C.; Rust, D.; Mehta, S.; Windt, E. d.; Sutherland, A.; Tomassini, J. E.; Dutko, F. J.; Deng, W.; Chen, X.; Tracy, L.; Zhou, H.; Millier, J. M.; Das, R. | | publishaheadofprint | - |
| medRxiv | 10.1101/2022.12.29.22284049 | 1 | 03/01/2023 | Immunogenicity and safety of Biological Es CORBEVAX vaccine as a heterologous booster dose in adult volunteers previously vaccinated with two doses of either COVISHIELD or COVAXIN: A Prospective double-blind randomised phase III clinical study | Thuluva, S.; Paradkar, V.; Gunneri, S.; Yerroju, V.; Mogulla, R. R.; Venkata Suneetha, P.; Turaga, K.; Binayke, A.; Zaheer, A.; Awasti, A.; Virkar, R.; Narang, M.; Nanjappa, P.; Mahantshetti, N.; Garg, B.; Mandal, R. | | publishaheadofprint | - |
| SSRN Electronic Journal | 10.2139/ssrn.4308756 | 1 | 01/01/2023 | Safety and Immunogenicity of Aerosolised Ad5-nCoV or Intramuscular Ad5-nCoV or Inactivated COVID-19 Vaccine Coronavac Given as the Second Booster Following Three Doses of CoronaVac: A Multicentre, Open-Label, Phase 4, Randomized Trial | Tang, Rong; Zheng, Hui; Wang, Bu-Sen; Gou, Jin-Bo; Guo, Xi-Ling; Chen, Xiao-Qin; Huang, Hai-Tao; Chen, Yin; Wu, Shi-Po; Li, Xiaolong; Zhong, Jin; Wang, Xue; Pan, Hong-Xing; Zhu, Jiahong; Wan, Peng; Xu, Xiao-Yu; Shi, Feng-Juan; Li, Zhuo-Pei; Liu, Jing-Xian; Zhang, Xiao-Yin; Cui, Lun-Biao; Song, Zhizhou; Zhu, Tao; Hou, Li-Hua; Zhu, Feng-Cai; Li, Jing-Xin | 10.1016/s2213-2600(23)00049-8 | initial deposit | CRESS |
| Research Square | 10.21203/rs.3.rs-2407050/v1 | 1 | 23/12/2022 | The efficacy and safety of an intranasal spray COVID-19 vaccine in a randomized double-blind placebo-controlled phase Ⅲ trial during Omicron period | Xia, Ningshao; Zhu, Fengcai; Huang, Shou-Jie; Liu, Xiaohui; Chen, Qi; Zhuang, Chunlan; Han, Jinle; Jaen, Anjuli; Do, Thai Hung; Peter, Jonathan; Dorado, Alexander; Tirador, Louie; Zabat, Gelza; Villalobos, Ralph; Gueco, Gemalyn; Botha, Lauren; Pertuz, Shirley; Tan, Jiaxiang; Zhu, Kongxin; Quan, Jiali; Lin, Hongyan; Huang, Yue; Jia, Jizong; Chu, Xiafei; Chen, Junyu; Chen, Yixin; Zhang, Tianying; Su, Ying-Ying; Li, Changgui; Ye, Xiangzhong; Wu, Ting; Zhang, Jun | | initial deposit | - |
| SSRN Electronic Journal | 10.2139/ssrn.4304730 | 1 | 22/12/2022 | Immunogenicity and Safety Assessment of a SARS-CoV-2 Recombinant Spike RBD Protein Vaccine (Abdala) in Paediatric Ages 3 to 18 Years Old: A Double-Blinded, Multicentre, Randomised, Phase 1/2 Clinical Trial (ISMAELILLO Study) | Cinza-Estévez, Zurina; Resik-Aguirre, Sonia; Figueroa-Baile, Nelvis Lázara; Oquendo-Martínez, Rachel; Campa-Legrá, Iván; Tejeda-Fuentes, Alina; Rivero-Caballero, Marila; González-García, Gloria; Chávez-Chong, Cristina Olimpia; Valdés, Marel A.; Hernández-Bernal, Francisco; Lemos-Pérez, Gilda; Campal-Espinosa, Ana; Freyre-Corrales, Giselle; Benítez-Gordillo, Delia; Gato-Orozco, Evelyn; Fraga-Quintero, Anitza; Pérez-Bartutis, Gretel Susana; Mesa-Pedroso, Iliana; Bueno-Alemañy, Nilda; Infante-Aguilar, Elizabeth; Rodríguez-Reinoso, José Luis; Melo-Suárez, Grettel; Limonta-Fernández, Miladys; Ayala-Ávila, Marta; Muzio-González, Verena L.; Group, ISMAELILLO Clinical Trial | | initial deposit | - |
| SSRN Electronic Journal | 10.2139/ssrn.4289473 | 1 | 06/12/2022 | Sarilumab Plus Standard of Care Versus Standard of Care for the Treatment of Severe COVID-19: A Phase 3, Randomized, Open-Labeled, Multi-Center Study (ESCAPE Study) | Mastrorosa, Ilaria; Gagliardini, Roberta; Segala, Francesco; Mondi, Annalisa; Lorenzini, Patrizia; Cerva, Carlotta; Taddei, Eleonora; Bai, Francesca; Vergori, Alessandra; Marcantonio, Negri; Pinnetti, Carmela; Cicalini, Stefania; Murri, Rita; Mazzotta, Valentina; Camici, Marta; Mosti, Silvia; Bini, Teresa; Maffongelli, Gaetano; Beccacece, Alessia; Milozzi, Eugenia; Iannetta, Marco; Lamonica, Silvia; Fusto, Marisa; Plazzi, Maria Maddalena; Ottou, Sandrine; Lichtner, Miriam; Fantoni, Massimo; Andreoni, Massimo; Sarmati, Loredana; Cauda, Roberto; Girardi, Enrico; Nicastri, Emanuele; D'Arminio Monforte, Antonella; Palmieri, Fabrizio; Cingolani, Antonella; Vaia, Francesco; Antinori, Andrea; Group, ESCAPE Study | 10.1016/j.eclinm.2023.101895 | initial deposit | CRESS |
| medRxiv | 10.1101/2022.11.21.22281000 | 1 | 22/11/2022 | Safety and immunogenicity of SARS-CoV-2 self-amplifying RNA vaccine expressing anchored RBD: a randomised, observer-blind, phase 1 study | AKAHATA, W.; Sekida, T.; Nogimori, T.; Ode, H.; Tamura, T.; Kono, K.; Kazami, Y.; Washizaki, A.; Masuta, Y.; Suzuki, R.; Matsuda, K.; Komori, M.; Morey, A.; Ishimoto, K.; Nakata, M.; Hasunuma, T.; Fukuhara, T.; Iwatani, Y.; Yamamoto, T.; Smith, J. F.; Sato, N. | 10.1016/j.xcrm.2023.101134 | publishaheadofprint | medRxiv |
| medRxiv | 10.1101/2022.11.20.22282565 | 1 | 22/11/2022 | Safety, Tolerability, and Immunogenicity of PIKA-Adjuvanted Re-combinant SARS-CoV-2 Spike (S) Protein Subunit Vaccine in Healthy Adults: Interim results of an open-label and randomised Phase 1 clinical trial. | Liu, Y.; Tan, L. H.; Zhang, N.; Zhang, Y.; Mojares, Z. R. | | publishaheadofprint | - |
| medRxiv | 10.1101/2022.11.18.22282414 | 1 | 20/11/2022 | Immunogenicity and safety of a 4th homologous booster dose of a SARS-CoV-2 recombinant spike protein vaccine (NVX-CoV2373): a phase 2, randomized, placebo-controlled trial | Alves, K.; Plested, J. S.; Galbiati, S.; Chau, G.; Cloney-Clark, S.; Zhu, M.; Kalkeri, R.; Patel, N.; Smith, K.; Marcheschi, A.; Pfeiffer, S.; McFall, H.; Smith, G.; Glenn, G. M.; Dubovsky, F.; Mallory, R. M. | | publishaheadofprint | - |
| Research Square | 10.21203/rs.3.rs-2273694/v1 | 1 | 14/11/2022 | Serial Viral Load Analysis by Ddpcr to Evaluate Fnc Efficacy and Safety in the Treatment of Mild Cases of Covid-19 | Cabral, Paula; Silva, Renato da; de Souza, Sávio; Arruda, Raul; Cabral, Sheila; de Assis, Arícia; Martins, Yolanda; Tavares, Carlos Augusto; Junior, Antônio Viana; Chang, Junbiao; Lei, Pingsheng | 10.3389/fmed.2023.1143485 | initial deposit | CRESS |
| medRxiv | 10.1101/2022.11.12.22282252 | 1 | 14/11/2022 | Early prone positioning does not improve the outcome of patients with mild pneumonia due to SARS-CoV-2: results from an open-label, randomized controlled trial (the EPCoT Study). | Fezzi, M.; Antolini, L.; Soria, A.; Bisi, L.; Iannuzzi, F.; Sabbatini, F.; Rossi, M.; Limonta, S.; Rugova, A.; Columpsi, P.; Squillace, N.; Foresti, S.; Pollastri, E.; Valsecchi, M. G.; Migliorino, G. M.; Bonfanti, P.; Lapadula, G. | 10.1183/23120541.00181-2023 | publishaheadofprint | medRxiv |
| medRxiv | 10.1101/2022.10.17.22281161 | 1 | 19/10/2022 | Clinical antiviral efficacy of remdesivir and casirivimab/imdevimab against the SARS-CoV-2 Delta and Omicron variants | Jittamala, P.; Schilling, W. H. K.; Watson, J. A.; Luvira, V.; Siripoon, T.; Ngamprasertchai, T.; Almeida, P. J.; Ekkapongpisit, M.; Cruz, C.; Callery, J. J.; Boyd, S.; Anunsittichai, O.; Hongsuwan, M.; Singhaboot, Y.; Pagornrat, W.; Tuntipaiboontana, R.; Kruabkontho, V.; Ngernseng, T.; Tubprasert, J.; Abdad, M. Y.; Keayarsa, S.; Madmanee, W.; Aguiar, R. S.; Santos, F. M.; Batty, E. M.; Hanboonkunupakarn, P.; Hanboonkunupakarn, B.; Sookprome, S.; Poovorawan, K.; Imwong, M.; Taylor, W. R.; Chotivanich, V.; Sangketchon, C.; Ruksakul, W.; Chotivanich, K.; Pukrittayakamee, S.; Dondorp, A. M.; Day, | | publishaheadofprint | - |
| medRxiv | 10.1101/2022.10.18.22281050 | 1 | 19/10/2022 | Interim Analysis of a Phase I Randomized Clinical Trial on the Safety and Immunogenicity of the mRNA-1283 SARS-CoV-2 Vaccine in Adults | Yassini, P.; Hutchens, M.; Paila, Y. D.; Schoch, L.; Aunins, A.; Siangphoe, U.; Paris, R. | 10.1080/21645515.2023.2190690 | publishaheadofprint | CRESS, medRxiv |
| medRxiv | 10.1101/2022.10.17.22281178 | 2 | 18/10/2022 | Fluvoxamine for Outpatient Treatment of COVID-19: A Decentralized, Placebo-controlled, Randomized, Platform Clinical Trial | McCarthy, M. W.; Naggie, S.; Boulware, D. R.; Lindsell, C. J.; Stewart, T. G.; Felker, G. M.; Jayaweera, D.; Sulkowski, M.; Gentile, N.; Bramante, C.; Singh, U.; Dolor, R. J.; Ruiz-Unger, J.; Wilson, S.; DeLong, A.; Remaly, A.; Wilder, R.; Collins, S.; Dunsmore, S. E.; Adam, S. J.; Thicklin, F.; Hanna, G.; Ginde, A. A.; Castro, M.; McTigue, K.; Shenkman, E.; Hernandez, A. F. | 10.1093/ofid/ofac492.1881 | publishaheadofprint | CRESS |
| SSRN Electronic Journal | 10.2139/ssrn.4237902 | 1 | 18/10/2022 | Molnupiravir Plus Usual Care Versus Usual Care Alone as Early Treatment for Adults with COVID-19 at Increased Risk of Adverse Outcomes (PANORAMIC): Preliminary Analysis from the United Kingdom Randomised, Controlled Open-Label, Platform Adaptive Trial | Butler, Christopher; Hobbs, F.D. Richard; Gbinigie, Oghenekome; Rahman, Najib M.; Hayward, Gail; Richards, Duncan; Dorward, Jienchi; Lowe, David; Standing, Joseph F.; Breuer, Judith; Khoo, Saye; Petrou, Stavros; Hood, Kerenza; Nguyen-Van-Tam, Jonathan S.; Patel, Mahendra; Saville, Benjamin R.; Marion, Joe; Ogburn, Emma; Allen, Julie; Rutter, Heather; Francis, Nick; Thomas, Nicholas; Evans, Philip; Dobson, Melissa; Madden, Tracie-Ann; Holmes, Jane; Harris, Victoria; Png, May Ee; Lown, Mark; van Hecke, Oliver; Detry, Michelle; Saunders, Christina; Fitzgerald, Mark; Berry, Nicholas; Mwandigha, Lazaro; Galal, Ushma; Jani, Bhautesh; Hart, Nigel; Butler, Daniel; Chalk, Jeremy; Lavallee, Layla; Hadley, Elizabeth; Cureton, Lucy; Benysek, Magdalena; Andersson, Monique; Coates, Maria; Barrett, Sarah; Bateman, Clare; Davies, Jennifer; Raymundo-Wood, Ivy; Ustianowski, Andrew; Carson-Stevens, Andrew; Yu, Ly-Mee; Little, Paul | 10.1016/s0140-6736(22)02597-1 | initial deposit | CRESS |
| Research Square | 10.21203/rs.3.rs-2167465/v1 | 1 | 14/10/2022 | Chlorpheniramine Intranasal Spray to Accelerate COVID-19 Clinical Recovery in an Outpatient Setting: The ACCROS Trials | Valerio-Pascua, Fernando; Mejia, Estela Jackeline Pineda; Tesch, Mari L.; Godoy, Jancy; Fuentes, Carlos López; Erazo, Gloria B.; Bermúdez, Marco; Pineda, Miguel Fernando Vargas; Rivzi, Syed A.A.; Cabrera, Armando; Chauhan, Zeeshan; Grullón-Franco, Scarlet; Paulino-Then, Jorge L.; Garcia, Natalia; Williams, Jeffrey D.; Rahaghi, Franck F. | | initial deposit | - |
| medRxiv | 10.1101/2022.10.10.22280850 | 1 | 13/10/2022 | Anti-SARS-CoV-2 antibody containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19 via increased neutralizing antibody activity. A randomized clinical trial | Denkinger, C. M.; Janssen, M.; Schaekel, U.; Gall, J.; Leo, A.; Stelmach, P.; Weber, S. F.; Krisam, J.; Baumann, L.; Stermann, J.; Merle, U.; Weigand, M. A.; Nusshag, C.; Bullinger, L.; Schrezenmeier, J.-F.; Bornhaeuser, M.; Alakel, N.; Witzke, O.; Wolf, T.; Vehreschild, M. J.; Schmiedel, S.; Addo, M. M.; Herth, F.; Kreuter, M.; Tepasse, P.-R.; Hertenstein, B.; Haenel, M.; Morgner, A.; Kiehl, M.; Hopfer, O.; Wattad, M.-A.; Schimanski, C. C.; Celik, C.; Pohle, T.; Ruhe, M.; Kern, W. V.; Schmitt, A.; Lorenz, H.-M.; Souto-Carneiro, M.; Gaeddert, M.; Halama, N.; Meuer, S.; Kraeusslich, H.-G.; Muel | 10.1038/s43018-022-00503-w | publishaheadofprint | CRESS |
| SSRN Electronic Journal | 10.2139/ssrn.4244749 | 1 | 13/10/2022 | Early suPAR-Guided Anakinra Treatment in COVID-19 Pneumonia: Subgroup Analyses and 90-Day Outcomes of the SAVE-MORE Trial | Akinosoglou, Karolina; Kotsaki, Antigone; Gounaridi, Ioanna-Maria; Christaki, Eirini; Metallidis, Simeon; Adamis, Georgios; Fragkou, Archontoula; Fantoni, Massimo; Rapti, Aggeliki; Kalomenidis, Ioannis; Chrysos, Georgios; Boni, Gloria; Kainis, Ilias; Alexiou, Zoi; Castelli, Francesco; Serino, Francesco Saverio; Bakakos, Petros; Nicastri, Emanuele; Tzavara, Vassiliki; Safarika, Asimina; Ioannou, Sofia; Dagna, Lorenzo; Dimakou, Katerina; Tzatzagou, Glykeria; Chini, Maria; Bassetti, Matteo; Kotsis, Vasileios; Angheben, Andrea; Tsoukalas, George; Selmi, Carlo; Spiropoulou, Olga-Maria; Samarkos, Michael; Doumas, Michael; Damoraki, Georgia; Masgala, Aikaterini; Papanikolaou, Ilias; Argyraki, Aikaterini; Negri, Marcantonio; Leventogiannis, Konstantinos; Symbardi, Styliani; Gatselis, Nikolaos K.; Petrakis, Vasileios; Netea, Mihai G.; Panagopoulos, Periklis; Sakka, Vissaria; Milionis, Haralampos; Dalekos, George; Giamarellos-Bourboulis, Evangelos | 10.1016/j.eclinm.2022.101785 | initial deposit | CRESS |
| SSRN Electronic Journal | 10.2139/ssrn.4243701 | 1 | 12/10/2022 | Therapeutic Combinations in Mild or Moderate COVID-19 to Reduce Nasopharyngeal Carriage of SARS-CoV-2 and Prevent Severe COVID-19 in Côte D’Ivoire: A Pragmatic Phase IIb Randomized Controlled Clinical Trial. The ANRS COV01 INTENSE-COV Trial | Bonnet, Fabrice; Doumbia, Adama; Machault, Vanessa; Ello, Frederic; Bellecave, Pantxika; Akpovo, Corinne; Sidibe, Baba; Fernandez, Laura; Koume, Antoine; Adjogoua, Edgard; Mireille, Dosso; Niangoran, Serge; Journot, Valerie; Eholié, Serge Paul | | initial deposit | - |
| SSRN Electronic Journal | 10.2139/ssrn.4238635 | 1 | 11/10/2022 | IP-10 Predicts Clinical Progression and Response to IL-6 Blockade with Sarilumab in Early COVID-19 Pneumonia. The SARICOR Clinical Trial | Trigo-Rodriguez, Marta; Cárcel, Sheila; Navas, Ana; Espíndola-Gómez, Reinaldo; Garrido-Gracia, José Carlos; Moreno, María Ángeles Esteban; León-López, Rafael; Pérez-Crespo, Pedro María Martínez; Aguilar Alonso, Eduardo; Vinuesa, David; Romero-Palacios, Alberto; Pérez-Camacho, Inés; Gutiérrez-Gutiérrez, Belén; Martínez-Marcos, Francisco Javier; Fernández-Roldán, Concepción; León, Eva; Caño, Alexandra Aceituno; Corzo, Juan E.; de la Fuente, Carmen; Jurado, Aurora; Torre-Cisneros, Julián; Merchante, Nicolás | 10.1093/ofid/ofad133 | initial deposit | CRESS |
| medRxiv | 10.1101/2022.10.08.22280836 | 1 | 10/10/2022 | GRAd-COV2 vaccine provides potent and durable immunity in a randomised placebo-controlled phase 2 trial (COVITAR) | Capone, S.; Fusco, F. M.; Milleri, S.; Borre', S.; Carbonara, S.; Lo Caputo, S.; Leone, S.; Gori, G.; Maggi, P.; Cascio, A.; Lichtner, M.; Cauda, R.; Dal Zoppo, S.; Cossu, M. V.; Gori, A.; Roda, S.; Confalonieri, P.; Bonora, S.; Missale, G.; Codeluppi, M.; Mezzaroma, I.; Capici, S.; Pontali, E.; Libanore, M.; Diani, A.; Lanini, S.; Battella, S.; Contino, A. M.; Piano Mortari, E.; Genova, F.; Parente, G.; Dragonetti, R.; Colloca, S.; Visani, L.; Iannacone, C.; Carsetti, R.; Folgori, A.; Camerini, R.; the COVITAR study group, | 10.1016/j.xcrm.2023.101084 | publishaheadofprint | medRxiv |
| medRxiv | 10.1101/2022.10.04.22280574 | 1 | 05/10/2022 | A randomized, placebo-controlled trial of a nasal spray solution containing broadly potent neutralizing antibodies against SARS-CoV-2 variants in healthy volunteers | Imsuwansri, T.; Jongthitinon, T.; Pojdoung, N.; Meesiripan, N.; Sakarin, S.; Boonkrai, C.; Wongtangprasert, T.; Phakham, T.; Audomsun, T.; Attakitbancha, C.; Saelao, P.; Muanwien, P.; Tian, M. T.; Tongchusak, S.; Sangruji, B.; Wannigama, D. L.; Sawangmake, C.; Rodprasert, W.; Le, Q. D.; Purbantoro, S. D.; Vasuntrarak, K.; Nantavisai, S.; Sirilak, S.; Uppapong, B.; Sapsutthipas, S.; Trisiriwanich, S.; Somporn, T.; Usoo, A.; Mingngamsup, N.; Phumiamorn, S.; Aumklad, P.; Arunprasert, K.; Patrojanasophon, P.; Opanasopit, P.; Pesirikan, N.; Nitisaporn, L.; Pitchayakorn, J.; Narkthong, T.; Mahong, B | | publishaheadofprint | - |
| medRxiv | 10.1101/2022.10.02.22280572 | 1 | 03/10/2022 | Immune responses of the third dose of AZD1222 vaccine or BNT162b2 mRNA vaccine after two doses of CoronaVac vaccines against Delta and Omicron variants | Niyomnaitham, S.; Jongkaewwattana, A.; Meesing, A.; Chusri, S.; Nanthapisal, S.; Hirankarn, N.; Siwamogsatham, S.; Kirdlarp, S.; Chaiwarith, R.; Lawpoolsri Niyom, S.; Thitithanyanont, A.; Hansasuta, P.; Pornprasit, K.; Chaiyaroj, S.; Pitisuttithum, P. | 10.1016/j.ijid.2023.01.022 | publishaheadofprint | CRESS |
| medRxiv | 10.1101/2022.09.22.22280247 | 1 | 26/09/2022 | Abatacept for Treatment of Adults Hospitalized with Moderate or Severe Covid-19 | Ko, E. R.; Anstrom, K. J.; Panettieri, R. A.; Lachiewicz, A. M.; Maillo, M.; O'Halloran, J.; Boucher, C.; Smith, P. B.; McCarthy, M. W.; Segura Nunez, P.; Mendivil Tuchia de Tai, S.; Khan, A.; Mena Lora, A. J.; Salathe, M.; Kedar, E.; Capo, G.; Rodriguez Gonzalez, D.; Patterson, T. F.; Palma, C.; Ariza, H.; Patelli Lima, M.; Blamoun, J.; Nannini, E.; Sprinz, E.; Mykietiuk, A.; Wang, J. P.; Parra-Rodriguez, L.; Der, T.; Willsey, K.; Benjamin, D. K.; Wen, J.; Zakroysky, P.; Halabi, S.; Silverstein, A.; McNulty, S. E.; O'Brien, S. M.; Al-Khalidi, H. R.; Butler, S.; Atkinson, J.; Adam, S. J.; Chan | 10.1093/ofid/ofac492.1877, 10.1093/ofid/ofac492.1884 | publishaheadofprint | CRESS |
| medRxiv | 10.1101/2022.09.22.22280245 | 2 | 23/09/2022 | Infliximab for Treatment of Adults Hospitalized with Moderate or Severe Covid-19 | O'Halloran, J.; Kedar, E.; Anstrom, K. J.; McCarthy, M. W.; Ko, E. R.; Segura Nunez, P.; Boucher, C.; Smith, P. B.; Panettieri, R. A.; Mendivil Tuchia de Tai, S.; Maillo, M.; Khan, A.; Mena Lora, A. J.; Salathe, M.; Capo, G.; Rodriguez Gonzalez, D.; Patterson, T. F.; Palma, C.; Ariza, H.; Patelli Lima, M.; Lachiewicz, A. M.; Blamoun, J.; Nannini, E.; Sprinz, E.; Mykietiuk, A.; Alicic, R.; Rauseo, A. M.; Wolfe, C. R.; Wittig, B.; Benjamin, D. K.; McNulty, S. E.; Zakroysky, P.; Halabi, S.; Butler, S.; Atkinson, J.; Adam, S. J.; Melsheimer, R.; Chang, S.; LaVange, L.; Proschan, M.; Bozzette, S. A | 10.1093/ofid/ofac492.1885 | publishaheadofprint | CRESS |
| medRxiv | 10.1101/2022.09.21.22280195 | 1 | 23/09/2022 | Efficacy and safety of convalescent plasma versus standard care in hospitalized patients with COVID-19 from the Peruvian Social Security Health System: open-label, randomized, controlled clinical trial | Villanueva, C.; Neyra, I.; Sagastegui, A.; Chunga, A.; Oyanguren, M.; Guillermo-Roman, M.; Soto-Ordonez, S.; Maguina, J. L.; Hurtado-Roca, Y.; Soto-Becerra, P.; Araujo-Castillo, R. V. | | publishaheadofprint | - |
| medRxiv | 10.1101/2022.09.20.22279903 | 1 | 21/09/2022 | Safety, Immunogenicity and Efficacy of NVX-CoV2373 in Adolescents in PREVENT-19: A Randomized, Phase 3 Trial | Anez, G.; Dunkle, L. M.; Gay, C. L.; Kotloff, K. L.; Adelglass, J. M.; Essink, B.; Campbell, J. D.; Cloney-Clark, S.; Zhu, M.; Plested, J. S.; Roychoudhury, P.; Greninger, A. L.; Patel, N.; McGarry, A.; Woo, W.; Cho, I.; Glenn, G. M.; Dubovsky, F. | 10.1093/ofid/ofac492.1869 | publishaheadofprint | CRESS |
| medRxiv | 10.1101/2022.09.15.22279897 | 1 | 15/09/2022 | Angiotensin 1-7 in severe COVID-19 patients: a phase 1 clinical trial | Valle Martins, A. L.; Annoni, F.; da Silva, F. A.; Bolais-Ramos, L.; Capanema de Oliveira, G.; dos Santos Matos, A. H.; Jardim Heyden, M. C.; Dias Pinheiro, B.; Abdo Rodrigues, N.; Alves Pereira, D. A.; Lana Diniz, M. M.; Granato Fonseca Silva, T.; Carvalho Cardoso, A.; Carvalho Martins, J.; Motta-Santos, D.; Campagnole-Santos, M. J.; Verano-Braga, T.; Taccone, F. S.; Santos, R. A. S. | | publishaheadofprint | - |
| SSRN Electronic Journal | 10.2139/ssrn.4213351 | 1 | 13/09/2022 | A Phase 3, Randomised, Double-Blind, Placebo-Controlled Clinical Trial for Adult Evaluation of the Efficacy and Safety of a Sars-Cov-2 Recombinant Spike Rbd Protein Vaccine (Abdala-3 Study) | Hernández-Bernal, Francisco; Ricardo-Cobas, Maria del Carmen; Martín-Bauta, Yenima; Rodríguez-Martínez, Ernesto; Urrutia-Pérez, Klaudia; Urrutia-Pérez, Karen; Quintana-Guerra, Joel; Navarro-Rodríguez, Zadis; Piñera-Martínez, Marjoris; Rodríguez-Reinoso, José Luis; Chávez-Chong, Cristina Olimpia; Baladrón-Castrillo, Idania; Melo-Suárez, Grettel; Batista-Izquierdo, Alejandro; Pupo-Micó, Alexis R.; Mora-Betancourt, Ricardo L.; Soler-Cano, Dayamí; Bizet-Almeida, Jacqueline; Martínez-Rodríguez, Maria C.; Lobaina-Lambert, Leonardo; Velázquez-Pérez, Vivian M.; Soler-Díaz, Jalimy; Blanco-Garrido, Yunaili; Laurencio-Vallina, Sandra; Meriño-Hechavarría, Tamara; Carmenaty-Campos, Norberto; Rodríguez-Montero, Enri; Limonta-Fernández, Miladys; Valdés, Marel A.; Hernández-Rodríguez, Reinier; Pimentel-Vázquez, Eulogio; Catasús-Álvarez, Karem M.; Cabrera-Núñez, Maria V.; Ayala-Ávila, Marta; Muzio-González, Verena L.; Investigators, ABDALA Group of | 10.1016/j.lana.2023.100497 | initial deposit | CRESS |
| SSRN Electronic Journal | 10.2139/ssrn.4214528 | 1 | 13/09/2022 | A Phase I, Prospective, Randomized, Open-Labeled Study to Evaluate the Safety, Tolerability, and Immunogenicity of Booster Dose with MVC-COV1901 or MVC-COV1901(Beta) SARS-CoV-2 Vaccine in Adults | Lien, Chia En; Liu, Ming-Che; Wang, Ning-Chi; Liu, Luke Tzu Chi; Wu, Chung-Chin; Tang, Wei-Hsuan; Lian, Wei-Cheng; Huang, Kuan-Ying A.; Chen, Charles | | initial deposit | - |
| Research Square | 10.21203/rs.3.rs-2061549/v1 | 1 | 13/09/2022 | Nasal anti-CD3 mAb (Foralumab) dampens CD3+ T effector function and decreases NKG7 in COVID-19 through a mechanism involving GIMAP-7 and TGFb1 | Moreira, Thais; Gauthier, Christian; Murphy, Liam; Lanser, Toby; Paul, Anu; Matos, Kimble; Mangani, Davide; Izzy, Saef; Rezende, Rafael; Healy, Brian; Baecher-Allan, Clare; Chitnis, Tanuja; Kuchroo, Vijay; Weiner, Howard | 10.1073/pnas.2220272120 | initial deposit | CRESS |
| SSRN Electronic Journal | 10.2139/ssrn.4216601 | 1 | 13/09/2022 | Transcranial Direct Current Stimulation (tDCS) for Post-COVID Fatigue: A Randomized, Double-Blind, Controlled Pilot Study | Oliver-Mas, Silvia; Delgado-Alonso, Cristina; Delgado-Álvarez, Alfonso; Díez-Cirarda, María; Cuevas, Constanza; Fernández-Romero, Lucía; Matias-Guiu, Andreu; Valles-Salgado, Maria; Gil, María José; Matias-Guiu, Jorge; Matias-Guiu, Jordi A. A. | 10.1093/braincomms/fcad117 | initial deposit | CRESS |
| medRxiv | 10.1101/2022.09.05.22279589 | 1 | 06/09/2022 | Safety and immunogenicity of a broad-spectrum mosaic vaccine as a booster dose against SARS-CoV-2 Omicron and other circulating variants | Kaabi, N. A.; Yang, Y. K.; Liang, Y.; Xu, K.; Zhang, X. F.; Kang, Y.; Jin, Y. Q.; Hou, J. W.; Zhang, J.; Yang, T.; Hussein, S.; ElDein, M. S.; Lei, Z. H.; Zhang, H.; Shao, S.; Liu, Z. M.; Liu, N.; Zheng, X.; Su, J. G.; Yang, S. S.; Cong, X. F.; Tan, Y.; Lei, W. W.; Gao, X. J.; Jiang, Z. W.; Wang, H.; Li, M.; Mekki, H. M.; Zaher, W.; Mahmoud, S.; Zhang, X.; Qu, C.; Liu, D. Y.; Zhang, J.; Yang, M. J.; Eltantawy, I.; Xiao, P.; Shen, F. J.; Wu, J. J.; Han, Z. B.; Du, L. F.; Tang, F.; Chen, S.; Ma, Z. J.; Zheng, F.; Hou, Y. N.; Li, X. Y.; Li, X.; Wang, Z. N.; Yin, J. L.; Mao, X. Y.; Zhang, J.; Qu, | 10.1038/s41392-022-01295-2 | publishaheadofprint | CRESS |
| SSRN Electronic Journal | 10.2139/ssrn.4201398 | 1 | 31/08/2022 | A Randomized, Double-Blind, Placebo-Controlled Phase I Trial of Inhalation Treatment of Recombinant TFF2/IFN Protein: A Multifunctional Candidate for Treatment of COVID-19 | Liu, Yan; Zhai, Guanxing; Fu, Weihui; Zhang, Xiaoyan; Xu, Jianqing | 10.3389/fphar.2022.1063106 | initial deposit | CRESS |
| medRxiv | 10.1101/2022.08.29.22279317 | 2 | 30/08/2022 | A Phase I, Prospective, Randomized, Open-labeled Study to Evaluate the Safety, Tolerability, and Immunogenicity of Booster Dose with MVC-COV1901 or MVC-COV1901(Beta) SARS-CoV-2 Vaccine in Adults | Lien, C. E.; Liu, M.-C.; Wang, N.-C.; Liu, L. T. -C.; Wu, C.-C.; Tang, W.-H.; Lian, W.-C.; Huang, K.-Y. A.; Chen, C. | 10.3390/vaccines11121798 | publishaheadofprint | medRxiv |
| medRxiv | 10.1101/2022.08.25.22279158 | 2 | 26/08/2022 | Homologous and heterologous boosting with CoronaVac and BNT162b2: a randomized trial (the Cobovax study) | Leung, N. H. L.; Cheng, S. M. S.; Cohen, C. A.; Martin-Sanchez, M.; Au, N. Y. M.; Luk, L. L. H.; Tsang, L. C. H.; Kwan, K. K. H.; Chaothai, S.; Fung, L. W. C.; Cheung, A. W. L.; Chan, K. C. K.; Li, J. K. C.; Ng, Y. Y.; Kaewpreedee, P.; Jia, J. Z.; Ip, D. K. M.; Poon, L. L. M.; Leung, G. M.; Peiris, M.; Valkenburg, S. A.; Cowling, B. J. | | publishaheadofprint | - |
| SSRN Electronic Journal | 10.2139/ssrn.4191606 | 1 | 26/08/2022 | Titers and Capacity of Neutralizing Antibodies Against SARS-CoV-2 Variants after Heterologous Booster Vaccination in Health Care Workers Primed with Two Doses of ChadOx1 nCov-19: A Single-Blinded, Randomized Clinical Trial | Chuang, Jack; Huang, Chung-Guei; Huang, Ching-Tai; Chen, Yi-Ching; Kung, Yu-An; Chen, Chih-Jung; Chuang, Tzu-Chun; Liu, Ching-Chi; Huang, Po-Wei; Yang, Shu-Li; Gu, Po-Wen; Shih, Shin-Ru; Chiu, Cheng-Hsun | 10.1016/j.jcv.2022.105328 | initial deposit | CRESS |
| medRxiv | 10.1101/2022.08.21.22279036 | 2 | 23/08/2022 | RNA polymerase inhibitor enisamium for treatment of moderate COVID- 19 patients: a randomized, placebo-controlled, multicenter, double-blind phase 3 clinical trial | Holubovska, O.; Babich, P.; Mironenko, A.; Milde, J.; Lebed, Y.; Stammer, H.; Mueller, L.; te Velthuis, A. J. W.; margitich, V.; Goy, A. | | publishaheadofprint | - |
| medRxiv | 10.1101/2022.08.17.22278748 | 2 | 21/08/2022 | A randomized, double-blind, Phase 1 study of IN-006, an inhaled antibody treatment for COVID-19 | Moench, T. R.; Botta, L.; Farrer, B.; Lickliter, J. D.; Kang, H.; Park, Y.; Kim, C.; Hoke, M.; Brennan, M.; McSweeney, M. D.; Richardson, Z.; Whelan, J. B.; Cho, J. M.; Lee, S. Y.; Faurot, F.; Hutchins, J.; Lai, S. K. | | publishaheadofprint | - |
| medRxiv | 10.1101/2022.08.18.22278867 | 1 | 21/08/2022 | LENZILUMAB OUTCOMES ACCORDING TO RACE OF COVID-19 PARTICIPANTS IN THE LIVE-AIR PHASE 3 TRIAL | Marconi, V.; Kilcoyne, A.; Cerasoli, F.; Polk, C.; Lewis, M.; Burger, C.; Jordan, E.; Durrant, C.; Chappell, D.; Temesgen, Z. | | publishaheadofprint | - |
| medRxiv | 10.1101/2022.08.09.22278560 | 1 | 12/08/2022 | Safety and Immunogenicity of a Recombinant Protein RBD Fusion Heterodimer Vaccine against SARS-CoV-2: preliminary results of a phase 1-2a dose-escalating, randomized, double-blind clinical trial. | Leal, L.; Pich, J.; Ferrer, L.; Nava, J.; Marti-Lluch, R.; Esteban, I.; Pradenas, E.; Raich-Regue, D.; Prenafeta, A.; Escobar, K.; Pastor, C.; Ribas-Aulinas, M.; Trinite, B.; Munoz-Basagoiti, J.; Domenech, G.; Clotet, B.; Corominas, J.; Corpes-Comes, A.; Garriga, C.; Barreiro, A.; Izquierdo-Useros, N.; Arnaiz, J. A.; Soriano, A.; Rios, J.; Nadal, M.; Plana, M.; Blanco, J.; Prat, T.; Torroella, E.; Ramos, R. | | publishaheadofprint | - |
| SSRN Electronic Journal | 10.2139/ssrn.4185918 | 1 | 12/08/2022 | Immunogenicity and Safety in Healthy Adults of Full-Dose Versus Half Doses of COVID-19 Vaccine (ChAdOx1-S or BNT162b2) or Full-Dose CoronaVac Administered as a Booster Dose after Priming with Coronavac: A Randomized, Observer-Blinded, Controlled Trial Conducted in Indonesia | Fadlyana, Eddy; Setiabudi, Djatnika; Putri, Nina Dwi; Sofiatin, Yulia; Suryadinata, Hendarsyah; Hartantri, Yovita; Sukandar, Hadyana; Indrati, Agnes R.; Murad, Chrysanti; Setiawaty, Vivi; Nur A Pangesti, Krisna; Multihartina, Pretty; Khrisna, Citra Vravita; Ayuninda, Masayu Riela; Wicaksana, Pratama; Zhafira, Aqila Sakina; Shinto, Robert; Kartasasmita, Cissy B.; Rusmil, Kusnandi; Hadinegoro, Sri Rezeki; Sundoro, Julitasari; Watts, Emma; Nguyen, Cattram D.; Mulholland, Kim | 10.1016/s1473-3099(22)00800-3 | initial deposit | CRESS |
| medRxiv | 10.1101/2022.08.09.22278329 | 3 | 10/08/2022 | COVID-19 convalescent plasma to treat hospitalised COVID-19 patients with or without underlying immunodeficiency | Lacombe, K.; Hueso, T.; Porcher, R.; Mekinian, A.; Chiarabini, T.; Georgin-Lavialle, S.; Ader, F.; Saison, J.; Martin-Blondet, G.; De Castro, N. A.; Bonnet, F.; Cazanave, C.; Francois, A.; Morel, P.; Hermine, O.; Pourcher, V.; Michel, M.; Lescure, X.; Soussi, N.; Brun, P.; Pommeret, F.; Sellier, P.; Rousset, S.; Piroth, L.; Michot, J.-M.; baron, g.; de Lamballerie, X.; Mariette, X.; Tharaux, P.-L.; Resche-Rigaux, M.; Ravaud, P.; Simon, T.; Tiberghien, P. | | publishaheadofprint | - |
| medRxiv | 10.1101/2022.08.05.22278464 | 1 | 08/08/2022 | Differential immune response induced by two immunization schedules with an inactivated SARS-CoV-2 vaccine in a randomized phase 3 clinical trial | Galvez, N. M. S.; CoronaVacCL03 Study Group, ; Pacheco, G. A.; Schultz, B. M.; Melo-Gonzalez, F.; Soto, J.; Duarte, L. F.; Gonzalez, L. A.; Rivera, D. S.; Rios, M.; Berrios, R. V.; Vazquez, Y.; Moreno-Tapia, D.; Vallejos, O. P.; Andrade, C. A.; Hoppe-Elsholz, G.; Iturriaga, C.; Urzua, M.; Navarrete, M. S.; Rojas, A.; Fasce, R.; Fernandez, J.; Mora, J.; Ramirez, E.; Gaete-Argel, A.; Acevedo, M.; Valiente-Echeverria, F.; Soto-Rifo, R.; Weiskopf, D.; Grifoni, A.; Sette, A.; Zeng, G.; Meng, W.; Gonzalez-Aramundiz, J. V.; Goldblatt, D.; Gonzalez, P. A.; Abarca, K.; Bueno, S. M.; Kalergis, A. M. | 10.7554/elife.81477 | publishaheadofprint | CRESS, medRxiv |