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| 10.1101/2022.05.17.22275027v1 | N/A | N/A | | N/A | | | 0 | 0 | 0 |
| 10.1101/2022.05.20.22275312v1 | N/A | N/A | | N/A | | | 0 | 0 | 0 |
| 10.21203/rs.3.rs-65224/v1 | N/A | N/A | | N/A | | | 0 | 0 | 0 |
| 10.2139/ssrn.4034179 | N/A | N/A | | N/A | | | 0 | 0 | 0 |
| 10.2139/ssrn.3975145 | N/A | N/A | | N/A | | | 0 | 0 | 0 |
| 10.2139/ssrn.3976701 | N/A | N/A | | N/A | | | 0 | 0 | 0 |
| 10.2139/ssrn.4031757 | N/A | N/A | | N/A | | | 0 | 0 | 0 |
| 10.2139/ssrn.3686447 | N/A | N/A | | N/A | | | 0 | 0 | 0 |
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| 10.1016/j.radonc.2021.12.024 | 25/12/2021 | Whole lung irradiation as a novel treatment for COVID-19: Final results of the prospective randomized trial (WINCOVID trial) | Radiotherapy and Oncology | Ganesan, Govindaraj; Ponniah, Sasipriya; Sundaram, Vivek; Marimuthu, Praveen Kumar; Pitchaikannu, Venkatraman; Chandrasekaran, Manikandan; Thangarasu, Janakiraman; Kannupaiyan, Gunasekaran; Ramamoorthy, Prabhu; Thangaraj, Brindha; Govindaraj, Harshavardhanan Sasipriya; Raguram, Shree Vaishnavi | 10 | 6 | 0 | 0 | 0 |
| 10.1016/j.eclinm.2021.101010 | 07/07/2021 | Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18 years or older: A randomized, double-blind, placebo-controlled, phase 1/2 trial | eClinicalMedicine | Guo, Wanshen; Duan, Kai; Zhang, Yuntao; Yuan, Zhiming; Zhang, Yan-Bo; Wang, Zejun; Zhao, Dongyang; Zhang, Huajun; Xie, Zhiqiang; Li, Xinguo; Peng, Cheng; Zhang, Wei; Yang, Yunkai; Chen, Wei; Gao, Xiaoxiao; You, Wangyang; Wang, Xue-Wei; Shi, Zhengli; Wang, Yanxia; Yang, Xu-Qin; Zhang, Lianghao; Huang, Lili; Wang, Qian; Lu, Jia; Yang, Yong-Li; Guo, Jing; Zhou, Wei; Wan, Xin; Wu, Cong; Wang, Wenhui; Du, Jianhui; Nian, Xuanxuan; Li, Xing-Hang; Huang, Shihe; Shen, Shuo; Xia, Shengli; Pan, An; Yang, Xiaoming | 32 | 20 | 0 | 0 | 0 |
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| 10.1101/2022.08.09.22278329 | 05/10/2023 | COVID-19 convalescent plasma to treat hospitalised COVID-19 patients with or without underlying immunodeficiency: a randomized trial | medRxiv | Lacombe, Karine; Hueso, Thomas; Porcher, Raphael; Mekinian, Arsène; Chiarabini, Thibault; Georgin-Lavialle, Sophie; Ader, Florence; Saison, Julien; Blondel, Guillaume Martin; De Castro, Nathalie; Bonnet, Fabrice; Cazanave, Charles; François, Anne; Morel, Pascal; Hermine, Olivier; Pourcher, Valérie; Michel, Marc; Lescure, Xavier; Soussi, Nora; Brun, Philippe; Pommeret, Fanny; Sellier, Pierre-Olivier; Rousset, Stella; Piroth, Lionel; Michot, Jean-Marie; Baron, Gabriel; De Lamballerie, Xavier; Mariette, Xavier; Tharaux, Pierre-Louis; Resche-Rigon, Matthieu; Ravaud, Philippe; Simon, Tabassome; Tiberghien, Pierre | 8 | 15 | 0 | 0 | 0 |
| 10.1101/2022.04.14.22272888 | 31/08/2023 | Nebulised dornase alfa reduces inflammation and improves clinical outcomes in severe COVID-19: a randomised clinical trial | medRxiv | Porter, Joanna C.; Inshaw, Jamie; Solis, Vincente Joel; Denneny, Emma; Evans, Rebecca; Temkin, Mia I.; De Vasconcelos, Nathalia; Aramburu, Iker Valle; Hoving, Dennis; Basire, Donna; Crissell, Tracey; Guinto, Jesusa; Webb, Alison; Esmail, Hanif; Johnston, Victoria; Last, Anna; Rampling, Thomas; Helbig, Elisa Theresa; Lippert, Lena; Kurth, Florian; Williams, Bryan; Flynn, Aiden; Lukey, Pauline T; Birault, Veronique; Papayannopoulos, Venizelos | 2 | 13 | 0 | 0 | 0 |
| 10.1101/2022.08.21.22279036 | 31/07/2023 | RNA polymerase inhibitor enisamium for treatment of moderate COVID-19 patients: a randomized, placebo-controlled, multicenter, double-blind phase 3 clinical trial | medRxiv | Holubovska, O.; Babich, P.; Mironenko, A.; Milde, J.; Lebed, Y.; Stammer, H.; Mueller, L.; te Velthuis, A.J.W.; Margitich, V.; Goy, A. | 0 | 3 | 0 | 0 | 0 |
| 10.2139/ssrn.4409350 | 07/04/2023 | Safety, Immunogenicity and Efficacy of Heterologous Boost with an Aerosolized Ad5-nCoV after Two-Dose Priming with Inactivated COVID-19 Vaccines in Adults: A Multicenter, Open-Label Trial | N/A | Li, Jing-Xin; Hou, Li-Hua; Gou, Jin-Bo; Jia, Si-Yue; Yin, Zun-Dong; Tang, Rong; Wu, Shi-Po; Wang, Fu-Zhen; Zhang, Zhe; Pan, Hong-Xing; Zhang, Li; Xu, Jia-Wei; Peng, Zhi-Hang; Tang, Ji-Hai; Wang, Qing; Xu, Qing; Zheng, Yan; Huang, Tao; Li, Tao; Liu, Shu-Jun; Wang, Cang-Ning; Zhu, Tao; Shen, Hong-Bing; Chen, Wei; Zhu, Feng-Cai | 0 | 0 | 0 | 0 | 0 |
| 10.1101/2023.01.31.23285306 | 31/03/2023 | Immunogenicity of the BA.1 and BA.4/BA.5 SARS-CoV-2 Bivalent Boosts: Preliminary Results from the COVAIL Randomized Clinical Trial | medRxiv | Branche, Angela R.; Rouphael, Nadine G.; Losada, Cecilia; Baden, Lindsey R.; Anderson, Evan J.; Luetkemeyer, Anne F.; Diemert, David J.; Winokur, Patricia L.; Presti, Rachel M.; Kottkamp, Angelica C.; Falsey, Ann R.; Frey, Sharon E.; Rupp, Richard; Bäcker, Martín; Novak, Richard M.; Walter, Emmanuel B.; Jackson, Lisa A.; Little, Susan J.; Immergluck, Lilly C.; Mahgoub, Siham M.; Whitaker, Jennifer A.; Babu, Tara M.; Goepfert, Paul A.; Fusco, Dahlene N.; Atmar, Robert L.; Posavad, Christine M.; Netzl, Antonia; Smith, Derek J.; Telu, Kalyani; Mu, Jinjian; Makowski, Mat; Makhene, Mamodikoe K.; Crandon, Sonja; Montefiori, David C.; Roberts, Paul C.; Beigel, John H. | 2 | 39 | 0 | 0 | 0 |
| 10.1101/2023.03.24.23287658 | 29/03/2023 | Safety and Immunogenicity of the NVX-CoV2373 Vaccine as a Booster in Adults Previously Vaccinated with the BBIBP-CorV Vaccine: An Interim Analysis | medRxiv | Toback, Seth; Marchese, Anthony M.; Warren, Brandy; Ayman, Sondos; Zarkovic, Senka; ElTantawy, Islam; Mallory, Raburn M.; Rousculp, Matthew; Almarzooqi, Fahed; Piechowski-Jozwiak, Bartlomiej; Bonilla, Maria-Fernanda; Bakkour, Agyad Ebrahim; Hussein, Salah Eldin; Kaabi, Nawal Al | 4 | 1 | 0 | 0 | 0 |
| 10.1101/2022.07.05.22277210 | 02/03/2023 | Safety and immunogenicity of the protein-based PHH-1V compared to BNT162b2 as a heterologous SARS-CoV-2 booster vaccine in adults vaccinated against COVID-19: a multicentre, randomised, double-blind, non-inferiority phase IIb trial | medRxiv | Corominas, Júlia; Garriga, Carme; Prenafeta, Antoni; Moros, Alexandra; Cañete, Manuel; Barreiro, Antonio; González-González, Luis; Madrenas, Laia; Güell, Irina; Clotet, Bonaventura; Izquierdo-Useros, Nuria; Raïch-Regué, Dàlia; Gallemí, Marçal; Blanco, Julià; Pradenas, Edwards; Trinité, Benjamin; Prado, Julia G; Blanch-Lombarte, Oscar; Pérez-Caballero, Raúl; Plana, Montserrat; Esteban, Ignasi; Pastor-Quiñones, Carmen; Núñez-Costa, Xavier; Taleb, Rachel Abu; McSkimming, Paula; Soriano, Alex; Nava, Jocelyn; Anagua, Jesse Omar; Ramos, Rafel; Lluch, Ruth Martí; Comes, Aida Corpes; Romero, Susana Otero; Gomez, Xavier Martinez; Sans-Pola, Carla; Moltó, José; Benet, Susana; Bailón, Lucía; Arribas, Jose R; Borobia, Alberto M; Parada, Javier Queiruga; Navarro-Pérez, Jorge; Forner Giner, Maria José; Lucas, Rafael Ortí; Vázquez Jiménez, María del Mar; Compán, Salvador Oña; Alvarez-Mon, Melchor; Troncoso, Daniel; Arana-Arri, Eunate; Meijide, Susana; Imaz-Ayo, Natale; García, Patricia Muñoz; de la Villa Martínez, Sofía; Fernández, Sara Rodríguez; Prat, Teresa; Torroella, Èlia; Ferrer, Laura | 3 | 70 | 0 | 0 | 0 |
| 10.1101/2023.01.24.23284869 | 22/02/2023 | A Randomized Trial Comparing Omicron-Containing Boosters with the Original Covid-19 Vaccine mRNA-1273 | medRxiv | Lee, Ivan T.; Cosgrove, Catherine A.; Moore, Patrick; Bethune, Claire; Nally, Rhiannon; Bula, Marcin; Kalra, Philip A.; Clark, Rebecca; Dargan, Paul I.; Boffito, Marta; Sheridan, Ray; Moran, Ed; Darton, Thomas C.; Burns, Fiona; Saralaya, Dinesh; Duncan, Christopher J. A.; Lillie, Patrick; Ramos, Alberto San Francisco; Galiza, Eva; Heath, Paul T.; Girard, Bethany; Parker, Christy; Rust, Dondi; Mehta, Shraddha; Windt, Elizabeth de; Sutherland, Andrea; Tomassini, Joanne E.; Dutko, Frank J.; Chalkias, Spyros; Deng, Weiping; Chen, Xing; Tracy, LaRee; Zhou, Honghong; Miller, Jacqueline M.; Das, Rituparna | 7 | 37 | 0 | 0 | 0 |
| 10.21203/rs.3.rs-2549560/v1 | 04/02/2023 | A randomized, controlled study to evaluate the safety and immunogenicity of a heterologous booster dose of an adjuvanted SARS CoV-2 recombinant spike protein vaccine in adults | Research Square | Kulkarni, Prasad; Gunale, Bhagwat; Kohli, Sunil; Lalwani, Sanjay; Tripathy, Srikanth; Kar, Sonali; Raut, Sidram; Kulkarni, Praveen; Apte, Aditi; Bavdekar, Ashish; Bhalla, Hira Lal; Plested, Joyce; Cloney-Clark, Shane; Zhu, MingZhu; Kalkeri, Raj; Pryor, Melinda; Hamilton, Stephanie; Thakar, Madhuri; Sannidhi, Ranga; Baranwal, Punjita; Bhamare, Chetanraj; Dharmadhikari, Abhijeet; Gupta, Manish; Poonawalla, Cyrus; Shaligram, Umesh; Kapse, Dhananjay | 1 | 6 | 0 | 0 | 0 |
| 10.2139/ssrn.4090492 | 31/01/2023 | Safety and Immunogenicity of an Inactivated Whole Virion SARS-CoV-2 Vaccine, TURKOVAC, in Healthy Adults: Interim Results from Randomised, Double-Blind, Placebo-Controlled Phase 1 and 2 Trials | N/A | Ozdarendeli, Aykut; Sezer, Zafer; Pavel, Shaikh Terkis Islam; Inal, Ahmet; Yetiskin, Hazel; Kaplan, Busra; Uygut, Muhammet Ali; Bayram, Adnan; Mazicioglu, Mumtaz; Kalin Unuvar, Gamze; Ture Yuce, Zeynep; Aydin, Guncu; Aslan, Ahmet Furkan; Kaya, Refika Kamuran; Koc, Rabia Cakir; Kara, Ates | 0 | 0 | 0 | 0 | 0 |
| 10.2139/ssrn.4309025 | 26/01/2023 | Safety and Immunogenicity of SARS-CoV-2 Self-Amplifying RNA Vaccine Expressing Anchored RBD: A Randomised, Observer-Blind, Phase 1 Study | N/A | Akahata, Wataru; Sekida, Takashi; Nogimori, Takuto; Ode, Hirotaka; Tamura, Tomokazu; Kono, Kaoru; Kazami, Yoko; Washizaki, Ayaka; Masuta, Yuji; Suzuki, Rigel; Matsuda, Kenta; Komori, Mai; Morey, Amber; Ishimoto, Keiko; Nakata, Misako; Hasunuma, Tomoko; Fukuhara, Takasuke; Iwatani, Yasumasa; Yamamoto, Takuya; Smith, Jonathan F.; Sato, Nobuaki | 0 | 0 | 0 | 0 | 0 |
| 10.1101/2022.12.29.22284049 | 03/01/2023 | Immunogenicity and safety of Biological E’s CORBEVAX™ vaccine as a heterologous booster dose in adult volunteers previously vaccinated with two doses of either COVISHIELD™ or COVAXIN: A Prospective double-blind randomised phase III clinical study | medRxiv | Thuluva, Subhash; Paradkar, Vikram; Gunneri, SubbaReddy; Yerroju, Vijay; Mogulla, Rammohan; Suneetha, Pothakamuri Venkata; Turaga, Kishore; Binayke, Akshay; Zaheer, Aymaan; Awasthi, Amit; Virkar, Rashmi; Narang, Manish; Nanjappa, Pradeep; Mahantshetti, Niranjana; Garg, BishanSwarup; Ravi, Mandal RavindraNath | 0 | 4 | 0 | 0 | 0 |
| 10.2139/ssrn.4308756 | 01/01/2023 | Safety and Immunogenicity of Aerosolised Ad5-nCoV or Intramuscular Ad5-nCoV or Inactivated COVID-19 Vaccine Coronavac Given as the Second Booster Following Three Doses of CoronaVac: A Multicentre, Open-Label, Phase 4, Randomized Trial | SSRN Electronic Journal | Tang, Rong; Zheng, Hui; Wang, Bu-Sen; Gou, Jin-Bo; Guo, Xi-Ling; Chen, Xiao-Qin; Huang, Hai-Tao; Chen, Yin; Wu, Shi-Po; Li, Xiaolong; Zhong, Jin; Wang, Xue; Pan, Hong-Xing; Zhu, Jiahong; Wan, Peng; Xu, Xiao-Yu; Shi, Feng-Juan; Li, Zhuo-Pei; Liu, Jing-Xian; Zhang, Xiao-Yin; Cui, Lun-Biao; Song, Zhizhou; Zhu, Tao; Hou, Li-Hua; Zhu, Feng-Cai; Li, Jing-Xin | 1 | 0 | 0 | 0 | 0 |
| 10.21203/rs.3.rs-2407050/v1 | 23/12/2022 | The efficacy and safety of an intranasal spray COVID-19 vaccine in a randomized double-blind placebo-controlled phase Ⅲ trial during Omicron period | Research Square | Xia, Ningshao; Zhu, Fengcai; Huang, Shou-Jie; Liu, Xiaohui; Chen, Qi; Zhuang, Chunlan; Han, Jinle; Jaen, Anjuli; Do, Thai Hung; Peter, Jonathan; Dorado, Alexander; Tirador, Louie; Zabat, Gelza; Villalobos, Ralph; Gueco, Gemalyn; Botha, Lauren; Pertuz, Shirley; Tan, Jiaxiang; Zhu, Kongxin; Quan, Jiali; Lin, Hongyan; Huang, Yue; Jia, Jizong; Chu, Xiafei; Chen, Junyu; Chen, Yixin; Zhang, Tianying; Su, Ying-Ying; Li, Changgui; Ye, Xiangzhong; Wu, Ting; Zhang, Jun | 2 | 9 | 0 | 0 | 0 |
| 10.2139/ssrn.4304730 | 22/12/2022 | Immunogenicity and Safety Assessment of a SARS-CoV-2 Recombinant Spike RBD Protein Vaccine (Abdala) in Paediatric Ages 3 to 18 Years Old: A Double-Blinded, Multicentre, Randomised, Phase 1/2 Clinical Trial (ISMAELILLO Study) | SSRN Electronic Journal | Cinza-Estévez, Zurina; Resik-Aguirre, Sonia; Figueroa-Baile, Nelvis Lázara; Oquendo-Martínez, Rachel; Campa-Legrá, Iván; Tejeda-Fuentes, Alina; Rivero-Caballero, Marila; González-García, Gloria; Chávez-Chong, Cristina Olimpia; Valdés, Marel A.; Hernández-Bernal, Francisco; Lemos-Pérez, Gilda; Campal-Espinosa, Ana; Freyre-Corrales, Giselle; Benítez-Gordillo, Delia; Gato-Orozco, Evelyn; Fraga-Quintero, Anitza; Pérez-Bartutis, Gretel Susana; Mesa-Pedroso, Iliana; Bueno-Alemañy, Nilda; Infante-Aguilar, Elizabeth; Rodríguez-Reinoso, José Luis; Melo-Suárez, Grettel; Limonta-Fernández, Miladys; Ayala-Ávila, Marta; Muzio-González, Verena L.; Group, ISMAELILLO Clinical Trial | 1 | 0 | 0 | 0 | 0 |
| 10.2139/ssrn.4289473 | 06/12/2022 | Sarilumab Plus Standard of Care Versus Standard of Care for the Treatment of Severe COVID-19: A Phase 3, Randomized, Open-Labeled, Multi-Center Study (ESCAPE Study) | SSRN Electronic Journal | Mastrorosa, Ilaria; Gagliardini, Roberta; Segala, Francesco; Mondi, Annalisa; Lorenzini, Patrizia; Cerva, Carlotta; Taddei, Eleonora; Bai, Francesca; Vergori, Alessandra; Marcantonio, Negri; Pinnetti, Carmela; Cicalini, Stefania; Murri, Rita; Mazzotta, Valentina; Camici, Marta; Mosti, Silvia; Bini, Teresa; Maffongelli, Gaetano; Beccacece, Alessia; Milozzi, Eugenia; Iannetta, Marco; Lamonica, Silvia; Fusto, Marisa; Plazzi, Maria Maddalena; Ottou, Sandrine; Lichtner, Miriam; Fantoni, Massimo; Andreoni, Massimo; Sarmati, Loredana; Cauda, Roberto; Girardi, Enrico; Nicastri, Emanuele; D'Arminio Monforte, Antonella; Palmieri, Fabrizio; Cingolani, Antonella; Vaia, Francesco; Antinori, Andrea; Group, ESCAPE Study | 0 | 0 | 0 | 0 | 0 |
| 10.1101/2022.11.20.22282565 | 22/11/2022 | Safety, Tolerability, and Immunogenicity of PIKA-Adjuvanted Recombinant SARS-CoV-2 Spike (S) Protein Subunit Vaccine in Healthy Adults: Interim results of an open-label and randomised Phase 1 clinical trial | medRxiv | Liu, Yuan; Tan, Lai Hock; Zhang, Nan; Zhang, Yi; Mojares, Zenaida Reynoso | 1 | 2 | 0 | 0 | 0 |
| 10.1101/2022.11.21.22281000 | 22/11/2022 | Safety and immunogenicity of SARS-CoV-2 self-amplifying RNA vaccine expressing anchored RBD: a randomised, observer-blind, phase 1 study | medRxiv | Akahata, Wataru; Sekida, Takashi; Nogimori, Takuto; Ode, Hirotaka; Tamura, Tomokazu; Kono, Kaoru; Kazami, Yoko; Washizaki, Ayaka; Masuta, Yuji; Suzuki, Rigel; Matsuda, Kenta; Komori, Mai; Morey, Amber; Ishimoto, Keiko; Nakata, Misako; Hasunuma, Tomoko; Fukuhara, Takasuke; Iwatani, Yasumasa; Yamamoto, Takuya; Smith, Jonathan F; Sato, Nobuaki | 1 | 320 | 0 | 0 | 0 |
| 10.1101/2022.11.18.22282414 | 20/11/2022 | Immunogenicity and safety of a 4<sup>th</sup>homologous booster dose of a SARS-CoV-2 recombinant spike protein vaccine (NVX-CoV2373): a phase 2, randomized, placebo-controlled trial | medRxiv | Alves, Katia; Plested, Joyce S; Galbiati, Shirley; Chau, Gordon; Cloney-Clark, Shane; Zhu, Mingzhu; Kalkeri, Raj; Patel, Nita; Smith, Kathy; Marcheschi, Alex; Pfeiffer, Susan; McFall, Heather; Smith, Gale; Glenn, Gregory M.; Dubovsky, Filip; Mallory, Raburn M. | 1 | 339 | 0 | 0 | 0 |
| 10.21203/rs.3.rs-2273694/v1 | 14/11/2022 | Serial Viral Load Analysis by Ddpcr to Evaluate Fnc Efficacy and Safety in the Treatment of Mild Cases of Covid-19 | Research Square | Cabral, Paula; Silva, Renato da; de Souza, Sávio; Arruda, Raul; Cabral, Sheila; de Assis, Arícia; Martins, Yolanda; Tavares, Carlos Augusto; Junior, Antônio Viana; Chang, Junbiao; Lei, Pingsheng | 2 | 19 | 0 | 0 | 0 |
| 10.1101/2022.11.12.22282252 | 14/11/2022 | Early prone positioning does not improve the outcome of patients with mild pneumonia due to SARS-CoV-2: results from an open-label, randomized controlled trial (the EPCoT Study) | medRxiv | Fezzi, Miriam; Antolini, Laura; Soria, Alessandro; Bisi, Luca; Iannuzzi, Francesca; Sabbatini, Francesca; Rossi, Marianna; Limonta, Silvia; Rugova, Alban; Columpsi, Paola; Squillace, Nicola; Foresti, Sergio; Pollastri, Ester; Valsecchi, Maria Grazia; Migliorino, Guglielmo Marco; Bonfanti, Paolo; Lapadula, Giuseppe; EPCoT Study Group | 0 | 3 | 0 | 0 | 0 |
| 10.1101/2022.10.17.22281178 | 01/11/2022 | Fluvoxamine for Outpatient Treatment of COVID-19: A Decentralized, Placebo-controlled, Randomized, Platform Clinical Trial | medRxiv | McCarthy, Matthew W.; Naggie, Susanna; Boulware, David R.; Lindsell, Christopher J.; Stewart, Thomas G.; Felker, G. Michael; Jayaweera, Dushyantha; Sulkowski, Mark; Gentile, Nina; Bramante, Carolyn; Singh, Upinder; Dolor, Rowena J.; Ruiz-Unger, Juan; Wilson, Sybil; DeLong, Allison; Remaly, April; Wilder, Rhonda; Collins, Sean; Dunsmore, Sarah E.; Adam, Stacey J.; Thicklin, Florence; Hanna, George; Ginde, Adit A.; Castro, Mario; McTigue, Kathleen; Shenkman, Elizabeth; Hernandez, Adrian F.; the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group | 11 | 273 | 0 | 0 | 0 |
| 10.1101/2022.10.17.22281161 | 19/10/2022 | Clinical antiviral efficacy of remdesivir and casirivimab/imdevimab against the SARS-CoV-2 Delta and Omicron variants | medRxiv | Jittamala, Podjanee; Schilling, William HK; Watson, James A; Luvira, Viravarn; Siripoon, Tanaya; Ngamprasertchai, Thundon; Almeida, Pedro J; Ekkapongpisit, Maneerat; Cruz, Cintia; Callery, James J; Boyd, Simon; Anunsittichai, Orawan; Hongsuwan, Maliwan; Singhaboot, Yutatirat; Pagornrat, Watcharee; Tuntipaiboontana, Runch; Kruabkontho, Varaporn; Ngernseng, Thatsanun; Tubprasert, Jaruwan; Abdad, Mohammad Yazid; Keayarsa, Srisuda; Madmanee, Wanassanan; Aguiar, Renato S; Santos, Franciele M; Batty, Elizabeth M; Hanboonkunupakarn, Pongtorn; Hanboonkunupakarn, Borimas; Sookprome, Sakol; Poovorawan, Kittiyod; Imwong, Mallika; Taylor, Walter RJ; Chotivanich, Vasin; Sangketchon, Chunlanee; Ruksakul, Wiroj; Chotivanich, Kesinee; Pukrittayakamee, Sasithon; Dondorp, Arjen M; Day, Nicholas PJ; Teixeira, Mauro M; Piyaphanee, Watcharapong; Phumratanaprapin, Weerapong; White, Nicholas J | 4 | 4 | 0 | 0 | 0 |
| 10.1101/2022.10.18.22281050 | 19/10/2022 | Interim Analysis of a Phase I Randomized Clinical Trial on the Safety and Immunogenicity of the mRNA-1283 SARS-CoV-2 Vaccine in Adults | medRxiv | Yassini, Patrick; Hutchens, Mark; Paila, Yamuna D.; Schoch, Lorraine; Aunins, Anne; Siangphoe, Uma; Paris, Robert | 0 | 41 | 0 | 0 | 0 |
| 10.2139/ssrn.4237902 | 18/10/2022 | Molnupiravir Plus Usual Care Versus Usual Care Alone as Early Treatment for Adults with COVID-19 at Increased Risk of Adverse Outcomes (PANORAMIC): Preliminary Analysis from the United Kingdom Randomised, Controlled Open-Label, Platform Adaptive Trial | SSRN Electronic Journal | Butler, Christopher; Hobbs, F.D. Richard; Gbinigie, Oghenekome; Rahman, Najib M.; Hayward, Gail; Richards, Duncan; Dorward, Jienchi; Lowe, David; Standing, Joseph F.; Breuer, Judith; Khoo, Saye; Petrou, Stavros; Hood, Kerenza; Nguyen-Van-Tam, Jonathan S.; Patel, Mahendra; Saville, Benjamin R.; Marion, Joe; Ogburn, Emma; Allen, Julie; Rutter, Heather; Francis, Nick; Thomas, Nicholas; Evans, Philip; Dobson, Melissa; Madden, Tracie-Ann; Holmes, Jane; Harris, Victoria; Png, May Ee; Lown, Mark; van Hecke, Oliver; Detry, Michelle; Saunders, Christina; Fitzgerald, Mark; Berry, Nicholas; Mwandigha, Lazaro; Galal, Ushma; Jani, Bhautesh; Hart, Nigel; Butler, Daniel; Chalk, Jeremy; Lavallee, Layla; Hadley, Elizabeth; Cureton, Lucy; Benysek, Magdalena; Andersson, Monique; Coates, Maria; Barrett, Sarah; Bateman, Clare; Davies, Jennifer; Raymundo-Wood, Ivy; Ustianowski, Andrew; Carson-Stevens, Andrew; Yu, Ly-Mee; Little, Paul | 32 | 0 | 0 | 0 | 0 |
| 10.21203/rs.3.rs-2167465/v1 | 14/10/2022 | Chlorpheniramine Intranasal Spray to Accelerate COVID-19 Clinical Recovery in an Outpatient Setting: The ACCROS Trials | Research Square | Valerio-Pascua, Fernando; Mejia, Estela Jackeline Pineda; Tesch, Mari L.; Godoy, Jancy; Fuentes, Carlos López; Erazo, Gloria B.; Bermúdez, Marco; Pineda, Miguel Fernando Vargas; Rivzi, Syed A.A.; Cabrera, Armando; Chauhan, Zeeshan; Grullón-Franco, Scarlet; Paulino-Then, Jorge L.; Garcia, Natalia; Williams, Jeffrey D.; Rahaghi, Franck F. | 1 | 26 | 0 | 0 | 0 |
| 10.1101/2022.10.10.22280850 | 13/10/2022 | Anti-SARS-CoV-2 antibody containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19 via increased neutralizing antibody activity – a randomized clinical trial | medRxiv | Denkinger, C.M.; Janssen, M.; Schäkel, U.; Gall, J.; Leo, A.; Stelmach, P.; Weber, S. F.; Krisam, J.; Baumann, L.; Stermann, J.; Merle, U.; Weigand, M. A.; Nusshag, C.; Bullinger, L.; Schrezenmeier, J.F.; Bornhäuser, M.; Alakel, N.; Witzke, O.; Wolf, T.; Vehreschild, M. J.G.T.; Schmiedel, S.; Addo, M. M.; Herth, F.; Kreuter, M.; Tepasse, P.-R.; Hertenstein, B.; Hänel, M.; Morgner, A.; Kiehl, M.; Hopfer, O.; Wattad, M.-A.; Schimanski, C. C.; Celik, C.; Pohle, T.; Ruhe, M.; Kern, W. V.; Schmitt, A.; Lorenz, H.M.; Souto-Carneiro, M.; Gaeddert, M.; Halama, N.; Meuer, S.; Kräusslich, H.G.; Müller, B.; Schnitzler, P.; Parthé, S.; Bartenschlager, R.; Gronkowski, M.; Klemmer, J.; Schmitt, M.; Dreger, P.; Kriegsmann, K.; Schlenk, R. F.; Müller-Tidow, C. | 5 | 10 | 0 | 0 | 0 |
| 10.2139/ssrn.4244749 | 13/10/2022 | Early suPAR-Guided Anakinra Treatment in COVID-19 Pneumonia: Subgroup Analyses and 90-Day Outcomes of the SAVE-MORE Trial | SSRN Electronic Journal | Akinosoglou, Karolina; Kotsaki, Antigone; Gounaridi, Ioanna-Maria; Christaki, Eirini; Metallidis, Simeon; Adamis, Georgios; Fragkou, Archontoula; Fantoni, Massimo; Rapti, Aggeliki; Kalomenidis, Ioannis; Chrysos, Georgios; Boni, Gloria; Kainis, Ilias; Alexiou, Zoi; Castelli, Francesco; Serino, Francesco Saverio; Bakakos, Petros; Nicastri, Emanuele; Tzavara, Vassiliki; Safarika, Asimina; Ioannou, Sofia; Dagna, Lorenzo; Dimakou, Katerina; Tzatzagou, Glykeria; Chini, Maria; Bassetti, Matteo; Kotsis, Vasileios; Angheben, Andrea; Tsoukalas, George; Selmi, Carlo; Spiropoulou, Olga-Maria; Samarkos, Michael; Doumas, Michael; Damoraki, Georgia; Masgala, Aikaterini; Papanikolaou, Ilias; Argyraki, Aikaterini; Negri, Marcantonio; Leventogiannis, Konstantinos; Symbardi, Styliani; Gatselis, Nikolaos K.; Petrakis, Vasileios; Netea, Mihai G.; Panagopoulos, Periklis; Sakka, Vissaria; Milionis, Haralampos; Dalekos, George; Giamarellos-Bourboulis, Evangelos | 0 | 0 | 0 | 0 | 0 |
| 10.2139/ssrn.4243701 | 12/10/2022 | Therapeutic Combinations in Mild or Moderate COVID-19 to Reduce Nasopharyngeal Carriage of SARS-CoV-2 and Prevent Severe COVID-19 in Côte D’Ivoire: A Pragmatic Phase IIb Randomized Controlled Clinical Trial. The ANRS COV01 INTENSE-COV Trial | SSRN Electronic Journal | Bonnet, Fabrice; Doumbia, Adama; Machault, Vanessa; Ello, Frederic; Bellecave, Pantxika; Akpovo, Corinne; Sidibe, Baba; Fernandez, Laura; Koume, Antoine; Adjogoua, Edgard; Mireille, Dosso; Niangoran, Serge; Journot, Valerie; Eholié, Serge Paul | 0 | 0 | 0 | 0 | 0 |
| 10.2139/ssrn.4238635 | 11/10/2022 | IP-10 Predicts Clinical Progression and Response to IL-6 Blockade with Sarilumab in Early COVID-19 Pneumonia. The SARICOR Clinical Trial | SSRN Electronic Journal | Trigo-Rodriguez, Marta; Cárcel, Sheila; Navas, Ana; Espíndola-Gómez, Reinaldo; Garrido-Gracia, José Carlos; Moreno, María Ángeles Esteban; León-López, Rafael; Pérez-Crespo, Pedro María Martínez; Aguilar Alonso, Eduardo; Vinuesa, David; Romero-Palacios, Alberto; Pérez-Camacho, Inés; Gutiérrez-Gutiérrez, Belén; Martínez-Marcos, Francisco Javier; Fernández-Roldán, Concepción; León, Eva; Caño, Alexandra Aceituno; Corzo, Juan E.; de la Fuente, Carmen; Jurado, Aurora; Torre-Cisneros, Julián; Merchante, Nicolás | 0 | 0 | 0 | 0 | 0 |
| 10.1101/2022.10.08.22280836 | 10/10/2022 | GRAd-COV2 vaccine provides potent and durable immunity in randomised placebo-controlled phase 2 trial (COVITAR) | medRxiv | Capone, Stefania; Fusco, Francesco M.; Milleri, Stefano; Borrè, Silvio; Carbonara, Sergio; Lo Caputo, Sergio; Leone, Sebastiano; Gori, Giovanni; Maggi, Paolo; Cascio, Antonio; Lichtner, Miriam; Cauda, Roberto; Dal Zoppo, Sarah; Cossu, Maria V.; Gori, Andrea; Roda, Silvia; Confalonieri, Paola; Bonora, Stefano; Missale, Gabriele; Codeluppi, Mauro; Mezzaroma, Ivano; Capici, Serena; Pontali, Emanuele; Libanore, Marco; Diani, Augusta; Lanini, Simone; Battella, Simone; Contino, Alessandra M.; Piano Mortari, Eva; Genova, Francesco; Parente, Gessica; Dragonetti, Rosella; Colloca, Stefano; Visani, Luigi; Iannacone, Claudio; Carsetti, Rita; Folgori, Antonella; Camerini, Roberto; COVITAR study group | 1 | 8 | 0 | 0 | 0 |
| 10.1101/2022.10.04.22280574 | 05/10/2022 | A randomized, placebo-controlled trial of a nasal spray solution containing broadly potent neutralizing antibodies against SARS-CoV-2 variants in healthy volunteers | medRxiv | Imsuwansri, Thanarath; Jongthitinon, Thitinan; Pojdoung, Niramon; Meesiripan, Nuntana; Sakarin, Siriwan; Boonkrai, Chatikorn; Wongtangprasert, Tossapon; Phakham, Tanapati; Audomsun, Thittaya; Attakitbancha, Chadaporn; Saelao, Pijitra; Muanwien, Phijitra; Tian, Maoxin Tim; Tongchusak, Songsak; Sangruji, Bhrus; Wannigama, Dhammika Leshan; Sawangmake, Chenphop; Rodprasert, Watchareewan; Le, Quynh Dang; Purbantoro, Steven Dwi; Vasuntrarak, Kananuch; Nantavisai, Sirirat; Sirilak, Supakit; Uppapong, Ballang; Sapsutthipas, Sompong; Trisiriwanich, Sakalin; Somporn, Thitiporn; Usoo, Asmah; Mingngamsup, Natthakarn; Phumiamorn, Supaporn; Aumklad, Porawan; Arunprasert, Kwanputtha; Patrojanasophon, Prasopchai; Opanasopit, Praneet; Pesirikan, Norapath; Nitisaporn, Ladda; Pitchayakorn, Jesada; Narkthong, Thana; Mahong, Bancha; Chaiyo, Kumchol; Srisuthisamphan, Kanjana; Viriyakitkosol, Ratchanont; Aeumjaturapat, Songklot; Jongkaewwattana, Anan; Bunnag, Sakarn; Pisitkun, Trairak | 1 | 76 | 0 | 0 | 0 |
| 10.1101/2022.10.02.22280572 | 03/10/2022 | Immune responses of the third dose of AZD1222 vaccine or BNT162b2 mRNA vaccine after two doses of CoronaVac vaccines against Delta and Omicron variants | medRxiv | Niyomnaitham, Suvimol; Jongkaewwattana, Anan; Meesing, Atibordee; Chusri, Sarunyou; Nanthapisal, Sira; Hirankarn, Nattiya; Siwamogsatham, Sarawut; Kirdlarp, Suppachok; Chaiwarith, Romanee; Niyom, Saranath Lawpoolsri; Thitithanyanont, Arunee; Hansasuta, Pokrath; Pornprasit, Kanokwan; Chaiyaroj, Sansanee; Pitisuttithum, Punnee | 1 | 19 | 0 | 0 | 0 |
| 10.1101/2022.09.22.22280245 | 26/09/2022 | Infliximab for Treatment of Adults Hospitalized with Moderate or Severe Covid-19 | medRxiv | O’Halloran, Jane A.; Kedar, Eyal; Anstrom, Kevin J.; McCarthy, Matthew W.; Ko, Emily R.; Nunez, Patricia Segura; Boucher, Cynthia; Smith, P. Brian; Panettieri, Reynold A.; de Tai, Sabina Mendivil Tuchia; Maillo, Martin; Khan, Akram; Mena Lora, Alfredo J.; Salathe, Matthias; Capo, Gerardo; Gonzalez, Daniel Rodríguez; Patterson, Thomas F; Palma, Christopher; Ariza, Horacio; Lima, Maria Patelli; Lachiewicz, Anne M.; Blamoun, John; Nannini, Esteban C.; Sprinz, Eduardo; Mykietiuk, Analia; Alicic, Radica; Rauseo, Adriana M.; Wolfe, Cameron R.; Witting, Britta; Benjamin, Daniel K.; McNulty, Steven E.; Zakroysky, Pearl; Halabi, Susan; Butler, Sandra; Atkinson, Jane; Adam, Stacey J.; Melsheimer, Richard; Chang, Soju; LaVange, Lisa; Proschan, Michael; Bozzette, Samuel A.; Powderly, William G.; ACTIV-1 IM study group members | 9 | 14 | 0 | 0 | 0 |
| 10.1101/2022.09.22.22280247 | 26/09/2022 | Abatacept for Treatment of Adults Hospitalized with Moderate or Severe Covid-19 | medRxiv | Ko, Emily R.; Anstrom, Kevin J.; Panettieri, Reynold A.; Lachiewicz, Anne M.; Maillo, Martin; O’Halloran, Jane A.; Boucher, Cynthia; Smith, P. Brian; McCarthy, Matthew W.; Segura Nunez, Patricia; Mendivil Tuchia de Tai, Sabina; Khan, Akram; Mena Lora, Alfredo J.; Salathe, Matthias; Kedar, Eyal; Capo, Gerardo; Rodríguez Gonzalez, Daniel; Patterson, Thomas F.; Palma, Christopher; Ariza, Horacio; Patelli Lima, Maria; Blamoun, John; Nannini, Esteban C.; Sprinz, Eduardo; Mykietiuk, Analia; Wang, Jennifer P.; Parra-Rodriguez, Luis; Der, Tatyana; Willsey, Kate; Benjamin, Daniel K.; Wen, Jun; Zakroysky, Pearl; Halabi, Susan; Silverstein, Adam; McNulty, Steven E.; O’Brien, Sean M.; Al-Khalidi, Hussein R.; Butler, Sandra; Atkinson, Jane; Adam, Stacey J.; Chang, Soju; Maldonado, Michael A.; Proscham, Michael; LaVange, Lisa; Bozzette, Samuel A.; Powderly, William G.; the ACTIV-1 IM study group members | 7 | 75 | 0 | 0 | 0 |
| 10.1101/2022.09.21.22280195 | 23/09/2022 | Efficacy and safety of convalescent plasma versus standard care in hospitalized patients with COVID-19 from the Peruvian Social Security Health System: open-label, randomized, controlled clinical trial | medRxiv | Villanueva, Cristian; Neyra, Ibeth; Sagastegui, Arturo; Chunga, Ausberto; Oyanguren, Martin; Guillermo-Roman, Martina; Soto-Ordoñez, Suly; Maguiña, Jorge L.; Hurtado-Roca, Yamilee; Soto-Becerra, Percy; Araujo-Castillo, Roger V. | 0 | 2 | 0 | 0 | 0 |
| 10.1101/2022.09.20.22279903 | 21/09/2022 | Safety, Immunogenicity and Efficacy of NVX-CoV2373 in Adolescents in PREVENT-19: A Randomized, Phase 3 Trial | medRxiv | Áñez, Germán; Dunkle, Lisa M.; Gay, Cynthia L.; Kotloff, Karen L.; Adelglass, Jeffrey M.; Essink, Brandon; Campbell, James D.; Cloney-Clark, Shane; Zhu, Mingzhu; Plested, Joyce S.; Roychoudhury, Pavitra; Greninger, Alexander L.; Patel, Nita; McGarry, Alice; Woo, Wayne; Cho, Iksung; Glenn, Gregory M.; Dubovsky, Filip; the 2019nCoV-301 – Pediatric Expansion Study Group | 8 | 36 | 0 | 0 | 0 |
| 10.1101/2022.09.15.22279897 | 15/09/2022 | Angiotensin 1-7 in severe COVID-19 patients: a phase 1 clinical trial | medRxiv | Valle Martins, Ana Luiza; Annoni, Filippo; da Silva, Filipe Alex; Bolais-Ramos, Lucas; Capanema de Oliveira, Gisele; dos Santos Matos, Alana Helen; Jardim Heyden, Maria Cecília; Pinheiro, Beatriz Dias; Rodrigues, Natália Abdo; Alves Pereira, Danilo Augusto; Lana Diniz, Mirella Monique; Granato Fonseca Silva, Thuanny; Cardoso, Alexandre Carvalho; Martins, Juliana Carvalho; Motta-Santos, Daisy; Campagnole-Santos, Maria José; Verano-Braga, Thiago; Taccone, Fabio Silvio; dos Santos, Robson Augusto Souza | 0 | 3 | 0 | 0 | 0 |
| 10.2139/ssrn.4213351 | 13/09/2022 | A Phase 3, Randomised, Double-Blind, Placebo-Controlled Clinical Trial for Adult Evaluation of the Efficacy and Safety of a Sars-Cov-2 Recombinant Spike Rbd Protein Vaccine (Abdala-3 Study) | SSRN Electronic Journal | Hernández-Bernal, Francisco; Ricardo-Cobas, Maria del Carmen; Martín-Bauta, Yenima; Rodríguez-Martínez, Ernesto; Urrutia-Pérez, Klaudia; Urrutia-Pérez, Karen; Quintana-Guerra, Joel; Navarro-Rodríguez, Zadis; Piñera-Martínez, Marjoris; Rodríguez-Reinoso, José Luis; Chávez-Chong, Cristina Olimpia; Baladrón-Castrillo, Idania; Melo-Suárez, Grettel; Batista-Izquierdo, Alejandro; Pupo-Micó, Alexis R.; Mora-Betancourt, Ricardo L.; Soler-Cano, Dayamí; Bizet-Almeida, Jacqueline; Martínez-Rodríguez, Maria C.; Lobaina-Lambert, Leonardo; Velázquez-Pérez, Vivian M.; Soler-Díaz, Jalimy; Blanco-Garrido, Yunaili; Laurencio-Vallina, Sandra; Meriño-Hechavarría, Tamara; Carmenaty-Campos, Norberto; Rodríguez-Montero, Enri; Limonta-Fernández, Miladys; Valdés, Marel A.; Hernández-Rodríguez, Reinier; Pimentel-Vázquez, Eulogio; Catasús-Álvarez, Karem M.; Cabrera-Núñez, Maria V.; Ayala-Ávila, Marta; Muzio-González, Verena L.; Investigators, ABDALA Group of | 1 | 0 | 0 | 0 | 0 |
| 10.21203/rs.3.rs-2061549/v1 | 13/09/2022 | Nasal anti-CD3 mAb (Foralumab) dampens CD3+ T effector function and decreases NKG7 in COVID-19 through a mechanism involving GIMAP-7 and TGFb1 | Research Square | Moreira, Thais; Gauthier, Christian; Murphy, Liam; Lanser, Toby; Paul, Anu; Matos, Kimble; Mangani, Davide; Izzy, Saef; Rezende, Rafael; Healy, Brian; Baecher-Allan, Clare; Chitnis, Tanuja; Kuchroo, Vijay; Weiner, Howard | 0 | 3 | 0 | 0 | 0 |